KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified manufacturing sites, providing global consistency and increased security of supply • Documented change control beyond CAS number, reducing risk of change • Non-phthalate and formulated without animal- derived substances • Standard concentrates in a PE carrier and on request in PP • Pre-colored formulations can be supplied in specific resins selected for the application REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) • Food contact established with FDA/EU* APPLICATION BULLETIN DRUG TYPE COLOR DESCRIPTION PANTONE REFERENCE AVIENT PRODUCT CODE PE BASED Adrenergic agonist combinations Light Green 373 C PE6M176349 Adrenergic agonists Purple 2583 C PE4M176057 Anti-infectives Tan 467 C PE8M176130 Anti-inflammatory, nonsteroidal Grey Cool Grey 4 C PE7M176184 Anti-inflammatory, steroids Pink 197 C PE3M176237 Anti-inflammatory, immunomodulators Olive Green 5763 C On request Beta-blockers Yellow Yellow C PE1M176160 Beta-blocker combinations Dark Blue 281 C PE5M176272 Carbonic anhydrase inhibitors Orange 1585 C PE2M176089 Cytotoxic Black 6 C PL9M176008 Miotics Dark Green 348 C PE6M176267 Mydriatics and cycloplegics Red 1797 C PE3M176236 Prostaglandin analogues Turquoise 326 C PE5M176273 Healthcare use limitations apply—see below.

Through our environmental aspect and impact assessments within our RC14001 EH&S Management System, we have focused on the following key topics: energy, emissions and climate change, as well as effluents and waste from our operations. Avient’s EH&S Committee of the Board of Directors provides oversight of the systems that are in place to monitor and mitigate risk associated with these key topics. Avient’s Corporate EH&S Department defines the strategy and monitors performance against related management system standards.

DB214 ORANGE FLO DM150DB REEBOK BLUE-S ORANGE

A/S ELITE CREAM PVC TRANS ORANGE NY UV ORANGE GOLD S NOLE

HIGH TEMP ORANGE HL1 LT FROST BEIGE S/UV WPP351 IX 030OR2054 ORANGE

S GREEN W/LM B S GREEN W/LM A CD 8802 ORANGE

is being promoted to the position of President of Performance Products & Solutions (PP&S).  He has played an instrumental role in the transformation of our Color segment, and I am excited to have him now lead PP&S." as he helped to build our PP&S team and further refine the segment's strategy toward specialty. 

Avient S. à r.l. Avient de Mexico Distribution S. de R.L. de C.V. Avient S. à r. l.

S. S. XRU-2311 GREEN S.