GLOBAL ISO 13485 MANUFACTURING FOOTPRINT Avient’s certified sites are located on three continents and offer manufacturing support, project transfer and back-up supply to reduce supply chain risk. COMPREHENSIVE REGULATORY TESTING AND DOCUMENTATION Raw materials tested to: • ISO 10993-1 and USP , (biological evaluation) • European Pharmacopeia 3.1.3/3.1.5 (polyolefin —materials used for the manufacture of containers) • USP (polyethylene—plastic materials of construction) • ICH Q3D (elemental impurities) We provide Drug Master File (Type III) documentation and other supporting regulatory declarations that are relevant for the application. They are manufactured at ISO 13485 certified sites with bio-compatible raw materials and documented change control.

TEMPERATURE, MPa Temperature (C) S tr en gt h (M M od ul us (G FLEXURAL MODULUS VS. TEMPERATURE, GPa Temperature (C) FLEXURAL FATIGUE STRENGTH, MPa Cycles to Failure (in thousands) F at iq ue S tr en gt h (M INSTALLATION INSTRUCTIONS Proper installation of composite springs from Avient is essential to achieve optimal performance and maximum service life. Hole diameters should be 1/32" (.8mm) larger in diameter than the diameter of mounting bolts.

Avient Colorants Germany GmbH Hohenrhein 1 56112 Lahnstein Germany Scope Production of Color Concentrates and Compounds Normative base ISO 50001:2018 Energy Management System Reg. no. 46089 Validity 17. 12. 2020 – 16. 12. 2023 Issue 12. 04. 2021 Swiss Made Swiss Association for Quality and Management Systems (SQS) Bernstrasse 103, 3052 Zollikofen, Switzerland sqs.ch F.

BLOOD LANCET MANUFACTURER S E A L I N G R I N G • Compliance with strict regulations for medical materials • Excellent sealing performance • Good compression set • Provided a recycled TPE solutions compared to silicone without increasing system cost • Delivered a TPE that complied with ISO 10993-4 & -5 and USP Class VI • Supported a change to an injection molded material to ease production and enhance assembly capabilities Versaflex™ HC TPEs – OM1040-1 Grade KEY REQUIREMENTS WHY AVIENT?

Zwolseweg 1, 2994 LB, Barendrecht, Netherlands. Park, Pudong, Shanghai China, 201203 and the sites as mentioned in the appendix accompanying this certificate has been found to conform to the Quality Management System standard: GB/T 19001-2016/ISO 9001:2015 This certificate is valid for the following scope: Design and Manufacture of Masterbatch Certificate No: 7071-1998-AQ-RGC-RvA Place and date: Shanghai, 19 March, 2021 Lack of fulfilment of conditions as set out in the Certification Agreement may render this Certificate invalid. ACCREDITED UNIT: DNV GL Business Assurance B.V., Zwolseweg 1, 2994 LB, Barendrecht, Netherlands.

Certificate Magna Colours Limited Certificate Of Conformance This is to certify that the Quality Management System of: Magna Colours Limited Unit 3 Dodworth Business Park, Dodworth Barnsley South Yorkshire S75 3SP United Kingdom has been assessed by ABS Quality Evaluations, Inc. and found to be in conformance with the requirements set forth by: ISO 9001:2015 The Quality Management System is applicable to: The Provision of a Service Of Sourcing, Procuring, Design, Manufacturing and Distribution of Specialty Colouration Products and Chemical Auxiliaries for use the Textile, Dying, Printing and Finishing Industries. Page 1 of 1 https://abs.zertic.com https://abs.zertic.com

Specifically, here are five ways TPEs can help the healthcare industry meet an anticipated capacity crunch: 1. In addition, the formulation meets ISO 15759 requirements for medical infusion equipment and is manufactured in an ISO 13485 facility.