Additionally, Avient’s ISO 13485 manufacturing site in Singapore for its Mevopur™ formulations recently achieved ISO/IEC 17025 accreditation for Biological Evaluation of Medical Devices–Part 5: Tests for In-Vitro Cytotoxicity.  Mevopur™ Healthcare Colorants and Functional Additives: formulations pre-tested to support compliance with regulatory requirements, such as USP Class VI, ISO 10993, EP3.1, USP661.1, and ICH Q3D and manufactured across a global network of ISO 13485-certified facilities or under GMP certifications. PCF values are available for these products and are based upon a TUV-certified ISO-14067: 2018 process.

DIN EN ISO 105-B06 DIN EN ISO 105-C04 DIN EN ISO 105-P02 DIN EN ISO 105-X12

DIN EN ISO 105-B06 DIN EN ISO 105-C04 DIN EN ISO 105-P02 DIN EN ISO 105-X12

DIN EN ISO 105-B06 DIN EN ISO 105-C04 DIN EN ISO 105-P02 DIN EN ISO 105-X12

USP Class VI and ISO 10993-4/5 compliant ASTM ISO Shore A/D ASTM/ISO %

Like other Mevopur products, they are formulated with raw materials tested to ISO 10993-1 and USP , European Pharmacopeia 3.1.3 and 3.1.5, USP and ICH Q3D.   Certified for USP Class VI and ISO 10993, the new Versaflex HC BIO BT218 grade is commercially available globally. Versaflex™ HC Thermoplastic Elastomers series HC3810: translucent TPE formulations offering excellent colorability for injection molded parts and over-molding, developed to comply with ISO 10993-4 and -5, REACH SVHC, and RoHS

KEY CHARACTERISTICS • Can be formulated for PESU, PPSU, and PSU • 43 standard colors as well as custom colors available • Ultra-high heat resistance • Based on raw materials pretested per ISO 10993 • Range of brilliant, vibrant colors • Based on raw materials compliant with food contact • Customizable with functional additive solutions • Based in polysulfone resins for ultra-high performance; may be formulated for other resin types • Low minimum order quantities available MARKETS AND APPLICATIONS Transcend colorants are formulated specifically for the healthcare market, and ideal for applications such as: • Dental tools and equipment • Surgical robots • Surgical lighting • Diagnostic equipment PRODUCT BULLETIN & COLOR CARD Colors may vary from actual color shown. NAME COLOR FAMILY COLOR CODE TRANSPARENTS Transparent Blue Violet Violet PPT6730-4005 Transparent Aquamarine Blue PPT6730-5018 Transparent Teal Green Green PPT6730-564C Transparent Optimal Yellow Yellow PPT6730-458C Transparent Energy Orange Orange PPT6730-150C Transparent Crimson Red PPT6730-2009 Transparent True Gray Gray PPT6730-7001 OPAQUES Linen White White PPO6730-9010 Hygienic White White PPO6730-9001 Ice Gray Gray PPO6730-5C True Gray Gray PPO6730-424C Shadow Gray PPO6730-446C Gunmetal Gray PPO6730-426C Black Black PPO6730-6C Powder Blue Blue PPO6730-2127C Smoky Blue Blue PPO6730-7682C Bright Azure Blue PPO6730-653C Cobalt Blue PPO6730-5002 Navy Blue PPO6730-5004 Aquamarine Blue PPO6730-7699C Blue Violet Violet PPO6730-7456C Emerald Green PPO6730-6016 Clover Green PPO6730-7723C Optimal Yellow Yellow PPO6730-459C Energy Orange Orange PPO6730-2000 Crimson Red PPO6730-3000 Colors may vary from actual color shown.

Standard colors for use in needle hubs (ISO 6009) Global network of ISO 13485 certified manufacturing sites ISO 6009 color range

Varies by Site; refer to ISO Cert https://www.avient.com/company/policies-and- governance/global-iso-certificate-library How often are 3rd party audits conducted? Procedures for requirements within ISO 9001 sites defined by business unit and Approved Corporate : Template/Form Document #: DOC-01879 Revision: 8 Document Owners: Brian Hoar Effective Date: May 13, 2022 Title: QF-02 Quality Standard Response Page 14 of 19 Only the electronic version of this document in ETQ is the controlled version of the document. IATF and ISO 13485 managed within ETQ Reliance.

For the plastics used in these medical applications, this can mean compliance with the relevant chapters of the International Organization for Standardization (ISO), the United States Pharmacopeia Class VI (USP VI) the European Pharmacopeia (EP 3.1), and the International Conference on Harmonization (ICH Q3D) standards and guidelines. All four sites are ISO 13485 certified and use a harmonized raw material range as the base for globally available Mevopur standard portfolios and for custom formulations. The raw materials are pre-tested to the relevant chapters of ISO 10991, USP 661, USP Class VI, EP 3.1 and to the ICH Q3D guidelines to help manufacturers increase the certainty of regulatory compliance for their devices and packaging.