REGULATORY SUPPORT • Drug delivery devices • Pharmaceutical packaging • Medical equipment KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing the risk of change • Allows crystallization in semi-crystalline polymers to begin faster and complete earlier REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 and USP biological evaluation - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities • Registered Drug Master File (Type III) and/or Device Master File • Food contact established with FDA/EU* APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

PRODUCT SPECIFICATION PRODUCT BULLETIN CARRIER PVC Recommended % of use 1% Temperature resistance 200°C Dispersion - abaque Avient ≤ 2 Copyright © 2022, Avient Corporation.

The additives are delivered as concentrates to use with a let- down ratio of typically 1 to 4% or as ready-to-use formulations to use without further dilution.

KEY CHARACTERISTICS • Manufactured at four ISO 13485 certified sites, providing global consistency and increased security of supply • Documented change control beyond CAS number level, reducing risk of change • Non-phthalate and formulated without animal-derived substances • Different tones of amber available on request —more or less red or yellow and/or lighter or darker • Also available in liquid form REGULATORY SUPPORT • Pre-tested raw materials: - ISO 10993-1 and USP parts (Class VI) - European Pharmacopeia, monograph 3.1.15, USP and elemental analysis as per ICH Q3D - USP criteria appearance of solution, color • Registered Drug Master File (Type III) by the FDA • Food contact compliance established with FDA/EU* • YBB00102002-2015 (oral liquid pharmaceutical PET bottles) compliance support APPLICATION BULLETIN * FDA/EU compliance information available upon request Healthcare use limitations apply—see below.

PMMA Considering lens performance, Resilience™ LS Frost PVC offers properties and material performance similar to PMMA, often at a significantly lower cost. 1 ASTM D-1003 measured by Polymer Diagnostics, Inc.

وتابعیھا ("البائع") تسري ھذه الشروط والأحكام على بیع آفینت كوربوریشن للمنتجات إلى ("مشتري") آخر 1. القبول. 1 ("الشروط") على جمیع مبیعات لبائع وھذه الشروط والأحكامالخاص باطلب ال الشروط والأحكام الحصریة للبیع، باستثناء ما یعُدل بموجب اتفاق وھيالبائع، خطي یوقعھ الأطراف. Terms and Conditions (1 April 2024) 2024أبریل 1(الشروط والأحكام(

وتابعیھا ("البائع") تسري ھذه الشروط والأحكام على بیع آفینت كوربوریشن للمنتجات إلى ("مشتري") آخر 1. القبول. 1 ("الشروط") على جمیع مبیعات لبائع وھذه الشروط والأحكامالخاص باطلب ال الشروط والأحكام الحصریة للبیع، باستثناء ما یعُدل بموجب اتفاق وھيالبائع، خطي یوقعھ الأطراف. Terms and Conditions (1 April 2024) 2024 أبریل 1(الشروط والأحكام(

Follow these two simple rules: 1. avient.ethicspoint.com 1-877-228-5410 (USA) Local in-country phone numbers are available at avient.ethicspoint.com Resources and Contact Information Our Policies You can get specific policy and contact information on our intranet site, The Loop in the Section: People & Departments, Ethics & Corporate Policies or from your supervisor or manager. OUR CODE OF INTEGRITY IN OUR CORPORATE SOCIAL CODE OF CONDUCT | 30 http://avient.ethicspoint.com http://avient.ethicspoint.com North America Global Headquarters Avon Lake, United States 33587 Walker Road Avon Lake, OH, United States 44012 Toll Free: +1 866 765 9663 Phone: +1 440 930 1000 Fax: +440 930 3064 Asia Pacific Regional Headquarters Shanghai, China 2F, Block C 200 Jinsu Road Pudong, 201206 Shanghai, China Telephone: +86 (0) 21 6028 4888 Fax: +86 (0) 21 6028 4999 South America Sao Paulo, Brazil Av.

Rachatewa, Bangplee Samutprakarn, Thailand, 10540 Phone: +66 232 791 00 Americas The ColorMatrix Corporation 680 North Rocky River Drive Berea, 44017 OH, USA Phone: +1 216 622 0100 Innovation Center & Manufacturing Plant 2900 Shawnee Industrial Way Suwanee, GA, United States, 30024 Phone: +1 770 271 5900 ColorMatrix do Brasil Indústria e Comércio de Pigmentos e Aditivos Ltda. 13295-000 Itupeva, SP Brazil Av.

Se viaggiate per lavoro siete tenuti a: 1. rispettare la politica di Avient su viaggi e intrattenimento; 2. mantenere un aspetto e una condotta che sostengano l’immagine e i valori fondamentali di Avient; 3. osservare tutte le leggi; e 4. segnalare e registrare tutte le spese vive aziendali dirette, ordinarie e opportune. Seguite queste due semplici regole: 1. non utilizzate informazioni sostanziali non pubbliche per un guadagno personale; e 2. non passate queste informazioni ad altre persone che non hanno la necessità di conoscerle nell’ambito del loro lavoro in Avient. Linea di assistenza telefonica sull’etica: https://www.Avient.com/company/policies-and-governance/ethics-hotline Numero della linea di assistenza telefonica sull’etica: 1-877-228-5410 https://www.Avient.com/company/policies-and-governance/ethics-hotline Nord America Sede globale Avon Lake, Stati Uniti 33587 Walker Road Avon Lake, Ohio, Stati Uniti 44012 Numero verde: +1 866 765 9663 Telefono: +1 440 930 1000 Fax: +1 440 930 3064 Asia Pacifico Sede regionale Shanghai, Cina 2F, Block C 200 Jinsu Road Pudong, 201206 Shanghai, Cina Telefono: +86 (0) 21 6028 4888 Fax: +86 (0) 21 6028 4999 America del Sud Sede regionale San Paolo, Brasile Av.