PDICaseStudy.indd 8.5 in 11.6875 in 8 .75 in 11.9375 in 8 .25 in 11 in PDI Solution Boosts Long-Term Medical Device Performance Spinal disc replacement manufacturer relies on quality analysis and manufacturing solutions from Polymer Diagnostics to help its breakthrough product reach far beyond durability requirements. Asset No. 76593C M Y K PDICaseStudy.indd REMAY 76593 trim: 8.5in x 11in and 8.25in x 11.6875in bleed: 8.75in x 11.9375in Digital/IAM 8.5 in 11.6875 in 8 .75 in 11.9375 in 8 .25 in 11 in www.polymerdiagnost ics.com Copyright © 2008, Polymer Diagnostics Inc.

KEY CHARACTERISTICS • Manufactured under change control principles beyond CAS number (similar level as MEVOPUR concentrates), reducing risk of change • Free from animal-derived substances and phthalates • Suitable for blown film, injection molding, blow molding and extrusion REGULATORY SUPPORT • Raw materials tested to: - ISO 10993-1 - USP chapters , including Class VI, a requirement for ophthalmic and nasal drugs - European Pharmacopeia 3.1.3/3.1.5 (polyolefin) - USP (polyethylene) - ICH Q3D elemental impurities - USP and USP light transmission • Registered Drug Master File (Type III) • Food contact compliance established with FDA/EU* APPLICATION BULLETIN CARRIER MATERIAL PIGMENT CONTENT/TYPE LIGHT FASTNESS THERMAL STABILITY PRODUCT CODE HDPE 50% TiO2 8 300°C PH00075525 LLDPE 60% TiO2 8 300°C PL00075542 LLDPE 70% TiO2 8 300°C PL00075545 PP 50% TiO2 8 300°C PP00075717 Healthcare use limitations apply—see below.

IMPROVED BOTTLE QUALITY +2% in neck +3% in body -12% in base 8.5g 0.5L bottle, 60% rPET Re-optimization of Polymer Weight Distribution to Improve Bottle Strength Based on commercially produced water bottles, 51,000bph Mechanical Strength Based on PTI 14.4g 0.5L water bottles, Instron testing To p Lo ad (l bs Burst Pressure Based on 8.5g, 0.5L commercially produced water bottles Bu rs t P re ss ur e (B ar REDUCED CO2 EMISSIONS 25% reduction in energy consumed during the bottle blowing process, based on a commercial process producing 8.5g 0.5L water bottles at 51,000 bph En er gy k W Reduced Energy Consumption ColorMatrix AAzure increases the heat-up rate for preforms, enabling energy reductions for the heating lamps used during the bottle blowing process. Melt processing of ColorMatrix AAzure products is carried out at typical PET processing conditions at recommended dose rates, which range from 0.01% to 0.13%. Care must be taken to optimize the bottle blowing process due to the increased heat- up rate of the preform, to take advantage of the many benefits offered by this product range.

PRODUCT BULLETIN EXCELITE - COMMON FORMULATIONS USAGE RATES Typically Excelite additives are dosed between 0.2% and 1.2% depending on the polymer, application and the density requirement. PRODUCTS APPLICATIONS DESCRIPTION/BENEFITS EXCELITE PF-1 PVC sheet for digital print or trimboard; Fine cell structure able to target low density: improves consistency and control over foaming process FOAM ADDITIVE-54 PVC sheet for digital print or trimboard; Finer cell structure than PF-1 promotes ultra smooth surface finish; improves consistency and control over foaming process PF-1E & FA-54E ADDITIVES PVC sheet for digital print or trimboard; Enhanced run time formulation reduces die lip build-up in PVC processes, leading to longer production run times FOAM ADDITIVE-33 CaZN formulations for PVC sheet, profile, or trimboard Promotes finer cell structure, higher cell density, and surface quality in CaZN PVC dryblends FOAM ADDITIVE-77 HDPE sheet & plastic lumber Industry-leading cell structure and cell density; achieves lower density without sacrificing quality; self-nucleating and able to increase extruder output rates up to 15% FOAM ADDITIVE-85 Endothermic foam or nucleating additive for olefin and styrene polymers; plastic lumber, sheet applications and food packaging products Can be used as a CFA or nucleating additive; nucleating capabilities promote fine cell structure and high cell density; achieves greater density reductions with more consistency and control FOAM ADDITIVE-37 HDPE sheet & plastic lumber Good cell structure and cell density in HDPE lumber; greater consistency and control over foaming process EXCELITE CAN IMPROVE PRODUCTION EFFICIENCY • The process operator has full control of density • Minimizes product rejection due to unnecessarily high/low density • Production should consistently target the bottom of the density specification • Enables control over the reintroduction of regrind or reprocessed materials as a feedstock • Enables the consistent foaming of products using higher percentages of regrind • Carrier selection can promote longer run times, enabling increased line productivity through less plate-out or material build-up on die lips EXCELITE CAN IMPROVE SURFACE FINISH Excelite additives creates a fine, consistent cell structure within the extruded polymer, which determine the surface roughness. This process allows greater control over production tolerances, thus reducing scrap rates, improving quality, and optimizing process capacity.

Bergamid™ FR Non-Halogen Flame Retardant Formulations: developed for high-voltage connectors, designed to combine the application flexibility of high-flow nylons for thin-wall designs with the sustainable performance of a non-halogenated fire retardant system, available in unfilled or reinforced PA6, PA66 and PA 6/66 grades with UL 94 V0 and CTI 800+ ratings  

Edgetek™ Engineered Polymer Formulations achieved a UL 94 V-0 flammability rating certification for server cabinets

Seat of the company 5/1. 9027 Győr, Mandulafa sor 3. 8. Date of the deed of foundation 8/1. 31 July 2018 8/2. 4 December 2019 Date of change: 2019/12/04 Effective: 2019/12/04 ... 8/3. 24 November 2021 902. TT 8.

identifikační číslo 26689537, sídlem Pobřežní 620/3, Karlín, 186 00 Praha 8, spisová značka C 87503 vedená u Městského soudu v Praze (dále též „Společnost“), o změně obsahu společenské smlouvy (dále též „Rozhodnutí“), konané dne 21.10.2021 v budově na adrese Jáchymova 26/2, Staré Město, 110 00 Praha 1. ------------------ I. 1. Kateřiny Hájkové, LL.M., datum narození 03.06.1982, adresa místa pobytu Křižíkova 220/91, Karlín, 186 00 Praha 8, advokáta, evidenční číslo ČAK 13682, spolupracujícího s PRK Partners s.r.o., advokátní kancelář, IČO 266 92 392, se sídlem Jáchymova 26/2, Staré Město, 110 00 Praha 1, dle kterého výpis z obchodního rejstříku obsahuje stav aktuální ke dni konání valné hromady dne 21.10.2021. ----------------------------------- 2. Kateřina Hájková, LL.M., datum narození 03.06.1982, adresa místa pobytu Křižíkova 220/91, Karlín, 186 00 Praha 8, advokáta, evidenční číslo ČAK 13682, spolupracujícího s PRK Partners s.r.o., advokátní kancelář, IČO 266 92 392, se sídlem Jáchymova 26/2, Staré Město, 110 00 Praha 1 (dále též „Předsedající“).

Industrial Design • Research methodologies • Brainstorming/problem solving • Concept sketching • Ergonomic development • 3D CAD modeling • Photo rendering & 3D prototyping • Color, material, & finish selection • Design for manufacturing Part/Tool/Process Design Optimization Prototype Capabilities • Over 10 injection molding machines ranging from 50–550 tons: - Materials sampling and evaluation • Fully automated continuous fiber reinforced thermoplastic (CFRTP) injection-overmolding cell - Prototyping combinations of injection molded discontinuous fiber reinforced thermoplastics with CFRTP inserts • Full suite of auxiliary support equipment including: - Material drying - Water and hot oil thermolators for mold heating - Ultrasonic welding for inserts - Secondary & post operations • 150-ton compression molding presses • Profile extrusion • Co-extrusion film and wire & cable • Over 20 molds at varying geometries to validate structural, application, and functional performance.

Industrial Design • Research methodologies • Brainstorming/problem solving • Concept sketching • Ergonomic development • 3D CAD modeling • Photo rendering & 3D prototyping • Color, material, & finish selection • Design for manufacturing Part/Tool/Process Design Optimization Prototype Capabilities • Over 10 injection molding machines ranging from 50–550 tons: - Customer prototype molding - Materials sampling and evaluation • Fully automated continuous fiber reinforced thermoplastic (CFRTP) injection-overmolding cell - Prototyping combinations of injection molded discontinuous fiber reinforced thermoplastics with CFRTP inserts • Full suite of auxiliary support equipment including: - Material drying - Water and hot oil thermolators for mold heating - Ultrasonic welding for inserts - Secondary & post operations • 150-ton compression molding presses • Profile extrusion • Over 20 molds at varying geometries to validate structural, application, and functional performance.